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Probiotics Premix for Anti-Aging & Inflammation Relief - China Suppliers & Factory | 500B Units

Deposite: CCTCC M 2020833

Shelf life: 24 months

Storage conditions: Stored at -18℃or lower

Health Benefits
Discover our premium quality products sourced directly from top manufacturers in China. As trusted suppliers, we ensure that each item meets rigorous standards for excellence and durability. Our factory employs advanced technology and skilled craftsmanship to deliver unparalleled value. Whether you're looking for innovative solutions or time-tested essentials, our selection from China meets diverse needs across various industries. Partner with us and experience the difference that comes from working with leading suppliers and factories in China
  • Bifidobacterium animalis subsp. lactis F1-7
  • Bifidobacterium animalis subsp. lactis KV9
  • Lactiplantibacillus plantarum YZX21
  • Lacticaseibacillus casei YRL577
  • Lacticaseibacillus paracasei X11
  • Lacticaseibacillus paracasei G15

Health Benefits

Reduce various inflammatory factors in the body
Relieve constipation
Improve diarrhea
Restore intestinal barrier
Increase abundance of beneficial bacteria in the gut

Bioyitech's Micro-Ecological Anti-Aging Solution

Anti-aging & Inflammation Relief ZC-AAI Probiotics Premix 500B

Probiotics (Bifidobacterium animalis subsp. lactis F1-7, Bifidobacterium animalis subsp. lactis KV9, Lacticaseibacillus paracasei X11, Lacticaseibacillus paracasei G15, Lacticaseibacillus casei YRL577, Lacticaseibacillus plantarum YZX21, and Lacticaseibacillus paracasei J5) synergistically regulate nutrient sensing, chronic inflammation, the mucosal immune barrier, and the gut-brain axis. This modulation of the gut microbiota aims to ameliorate age-related diseases, thereby achieving anti-aging effects and promoting health.

F1-7/YZX21 elevates GLP-1 and PYY levels, thereby stimulating insulin secretion in a glucose-dependent manner

Anti-aging & Inflammation Relief ZC-AAI Probiotics Premix 500B2

Experiments with Lactobacillus F1-7/Plant YZX21 Related Strains
Control: Hyperglycaemia group | Rhamnose LGG: Probiotics group
Bifidobacterium lactis F1-7: Probiotics group | Plant YZX21: Probiotics group

Role of F1-7, YZX21:
Increase the level of GLP-1, thus promoting the release of insulin from the pancreas, blocking glucagon secretion, and lowering postprandial blood glucose.

G15 modulates glycemia by upregulating GRP43 and secreting GLP-1/PYY

Anti-aging & Inflammation Relief ZC-AAI Probiotics Premix 500B3

GPR41 and GPR43 are two specific short-chain fatty acid receptors that have been discovered so far. They can enhance the secretion of GLP-1 in the primary colon. G15 and Q14 significantly increase the expression of GPR43 by approximately 1.5 times.

Compared with the control group, G15 and Q14 significantly increased the concentrations of GLP-1 and PYY, and had similar regulatory effects to metformin treatment, which was helpful to improve blood glucose homeostasis and insulin sensitivity.

Anti-aging & Inflammation Relief ZC-AAI Probiotics Premix 500B4

Conclusion: G15 parietal cheese can effectively improve glucose tolerance and prevent hyperglycaemia in patients with type II diabetes mellitus.

① (B/b) glucose tolerance is a recognised diagnostic criterion for insulin resistance in T2D. After 6 weeks of treatment, glucose tolerance was effectively restored in all treatment groups.
② (C/D) Insulin and glucagon are sensitive parameters for the diagnosis of diabetes mellitus and reference indexes for blood glucose control, and G15 reduced insulin and glucagon concentrations to a large extent.
Anti-aging & Inflammation Relief ZC-AAI Probiotics Premix 500B5

Conclusion: The protein expression level of MUC-2 was lowest in the model group and significantly increased in the normal and intervention groups.

The most significant up-regulation of MUC-2 protein level was found after the intervention of KGM+F1-7 combination.

Anti-aging & Inflammation Relief ZC-AAI Probiotics Premix 500B6

Serum levels of the endotoxin LPS are considered to be a potential indicator of increased intestinal permeability and are strongly correlated with intestinal permeability.

As shown in the figure, serum endotoxin levels were significantly increased in the sham group compared to the OVX group, demonstrating that estrogen deficiency increases intestinal permeability.

Both significantly reduced serum endotoxin levels (p<0.05) by probiotic F1-7 intervention, which further suggests that probiotic F1-7 reduced intestinal permeability.

Lacticaseibacillus paracasei X11 can repair intestinal tissue

Anti-aging & Inflammation Relief ZC-AAI Probiotics Premix 500B7

Compared to the control group, the model group's intestinal tract exhibited a loss of structural integrity, with disordered intestinal epithelial folds and a near-complete disappearance of the muscularis externa. In contrast, the intervention group displayed relatively regular intestinal mucosal folds and an intact muscularis externa.

Anti-aging & Inflammation Relief ZC-AAI Probiotics Premix 500B8

Studies have shown that F1-7 has a significant anti-inflammatory effect.
Schematic diagram of histochemistry of the expression of inflammatory factor-related indexes in the aorta of mice, using AS as a control:

Groups F1-7: TLR4-positive areas were significantly reduced, reducing the expression content of MYD88 in the aortic sinus and improving inflammatory expression; Group KO: TLR4-positive areas were significantly reduced, reducing the expression content of MYD88 in the aortic sinus and improving inflammatory expression.

Group KF: The most significant reduction of TLR4-positive areas was achieved, reducing the expression content of MYD88 in the aortic sinus had the most significant effect and improving inflammatory expression.

Frequently Asked Questions (FAQ)

What are the primary health benefits of Bioyitech's probiotics?

Bioyitech's probiotics help reduce various inflammatory factors in the body, relieve constipation, improve diarrhea, restore the intestinal barrier, and increase the abundance of beneficial bacteria in the gut.

How does the anti-aging probiotic premix work?

The premix contains a synergistic blend of probiotics (such as Bifidobacterium animalis subsp. lactis F1-7, Lacticaseibacillus paracasei X11, G15, and others) that regulate nutrient sensing, chronic inflammation, the mucosal immune barrier, and the gut-brain axis to ameliorate age-related conditions.

How do the F1-7 and YZX21 strains help manage blood glucose?

These specific strains elevate GLP-1 and PYY levels, which stimulates glucose-dependent insulin secretion from the pancreas, blocks glucagon secretion, and helps lower postprandial blood glucose levels.

What role does Lacticaseibacillus paracasei G15 play in diabetes management?

G15 modulates glycemia by upregulating short-chain fatty acid receptors like GRP43 and secreting GLP-1/PYY. Studies show it can effectively restore glucose tolerance, lower insulin and glucagon concentrations, and prevent hyperglycaemia.

Can these probiotics repair the intestinal lining?

Yes, Lacticaseibacillus paracasei X11 has been shown to repair damaged intestinal tissue, restoring structural integrity, regular mucosal folds, and an intact muscularis externa compared to control models.

Does probiotic F1-7 help reduce intestinal permeability and inflammation?

Yes, intervention with probiotic F1-7 significantly reduces serum endotoxin (LPS) levels, indicating reduced intestinal permeability. It also reduces TLR4-positive areas and MYD88 expression, showing strong anti-inflammatory effects in the aortic sinus.

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