Uric Acid Reduction Probiotics Premix - China Suppliers & Factory for Gout Relief and Clinical Research
Deposite: CCTCC M 2020833
Shelf life: 24 months
Storage conditions: Stored at -18℃or lower
Health Benefits
Functional Strains
Lacticaseibacillus paracasei X11
Lacticaseibacillus paracasei Lpc-C66
Bifidobacterium animalis subsp. lactis KV9
Bifidobacterium animalis subsp. lactis F1-7
Main Functions
Reduce purine intake
Alleviate gout symptoms
Improve hepatic and renal metabolism
Clinical Research Institution: Guangdong Second Provincial Hospital – a Tertiary Grade A Hospital
Clinical registration number: ChiCTR2500096029—A randomized, double-blind, placebo-controlled feeding study of compound Lactobacillus powder in patients with hyperuricemia (with or without gout).
Uric acid decreased by ~20% (max -207 μmol/L) within 8 weeks
Gout attacks reduced by 47% (duration shortened by 69%)
Reduced use of emergency gout medications
No. 1 in China · Collaboration with Grade III Class A Hospital · Clinically Evidenced Functional Probiotic Strain
A Randomized, Double-blind, Placebo-controlled Feeding Trial of Purineed™ Premix Probiotics Powder in Patients with Hyperuricemia (With or Without Gout).
Research Institution
Guangdong Second Provincial General Hospital (a Grade III, Level A general hospital)
Total Sample Size
50 patients with hyperuricemia (with or without gout) (mean serum uric acid level: 554 μmol/L)
Intervention Duration
8 consecutive weeks of trial consumption
Primary Efficacy Indicators
Changes in serum uric acid levels, frequency of acute gout attacks, and use of emergency medication for acute gout attacks, etc.
Intervention Protocol
2g, twice daily
Clinical Data 1: Changes observed over 8 weeks, with 72% of subjects showing a decrease in serum uric acid levels.
Trial Notes: The 8-week trial demonstrated that Purineed™ exhibited a significant uric acid-lowering effect. 72% of the subjects experienced a reduction in uric acid levels, with the decrease generally around 20%. Serum uric acid levels decreased by up to 207 μmol/L, significantly lower than individual baseline values.
Clinical Data 2: Gout attack frequency was reduced by 47%, and the attack duration was shortened by 69%.
Trial Notes: Compared to the control group, Purineed™ significantly reduced the frequency of acute gout attacks by 47% and shortened the attack duration by approximately 69% (representing a 3.3-fold relative improvement in efficacy). This indicates that Purineed™ can effectively decrease the frequency of gout flare-ups and mitigate the severity of acute attacks, aiding in recovery.
Clinical Data 3: Reduced Medication Use – 100% of Users Required No Emergency Gout Medication
Trial Notes: After 8 weeks of trial consumption, the number of emergency medication uses in the test group was zero. 100% of the subjects in the test group did not require emergency medication due to acute gout attacks. This indicates that Purineed™ can effectively help individuals with hyperuricemia/gout avoid acute gout attacks, thereby reducing or even eliminating the need for emergency medication.
Purineed™ Premix Probiotics powder has been shown to lower serum uric acid levels, significantly reduce reliance on emergency gout medication, decrease the frequency of gout attacks, and shorten their duration. The effects demonstrated potential sustainability, and the product exhibited a favorable overall safety profile.
*The above is a data excerpt. For detailed clinical reports, please consult Zhongchuang Yike (Shanghai) Biotechnology Co., Ltd. at 400-166-7858.
Frequently Asked Questions (FAQ)
What functional probiotic strains are used in Purineed™?
Purineed™ contains a proprietary blend of four functional probiotic strains: Lacticaseibacillus paracasei X11, Lacticaseibacillus paracasei Lpc-C66, Bifidobacterium animalis subsp. lactis KV9, and Bifidobacterium animalis subsp. lactis F1-7.
How does Purineed™ help alleviate hyperuricemia and gout?
Purineed™ works through three primary mechanisms: reducing purine intake, alleviating gout symptoms, and improving hepatic and renal metabolism to assist in uric acid regulation.
What were the clinical findings regarding uric acid reduction?
In an 8-week clinical trial, 72% of the subjects demonstrated a decrease in serum uric acid levels, with an average reduction of nearly 20%. The maximum recorded reduction reached 207 μmol/L.
Can Purineed™ reduce the frequency and duration of gout attacks?
Yes, clinical results showed that the frequency of gout attacks was reduced by 47%, and the overall duration of the attacks was shortened by approximately 69%.
Does this probiotic formula reduce the need for emergency gout medications?
During the 8-week clinical trial, 100% of the subjects in the test group did not require emergency medication, effectively reducing the emergency medication usage rate to zero.