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Weight Management Probiotics Premix 500B – Trusted China Suppliers and Factory for Quality Supplements

Deposite: CCTCC M 2020833

Shelf life: 24 months

Storage conditions: Stored at -18℃or lower

Health Benefits
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    Main Strains

    Lactiplantibacillus plantarum F3-2
    Lactiplantibacillus plantarum H-87
    Lactiplantibacillus plantarum YZX21
    Lacticaseibacillus casei YRL577
    Lacticaseibacillus paracasei G15
    Bifidobacterium animalis subsp. lactis BA-C53
    📅 Shelf life: 24 months
    ❄️ Storage conditions: Stored at -18℃ or below

    Health Benefits

    Lower body weight and BMI
    Reduce waist circumference
    Reduce visceral fat
    Relieve high fat diet-induced obesity
    Reduce your food intake

    The advantages of probiotics in fat-lowering

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    Experiment on Bifidobacterium animalis subsp. lactics F1-7 and Lactiplantibacillus plantarum YZX21

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    Conclusion:

    F1-7 and YZX21 increase the level of GLP-1, thus promoting the secretion of insulin in the body, and up-regulate glucagon gene, regulate blood sugar bidirectional, and relieve the phenomenon of hyperglycemia or hypoglycemia.

    Lactiplantibacillus plantarum F3-2 showed significant improvement in body fat

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    The data presented in the figure indicates that after a period of feeding, the body weight of mice in the high-fat diet group significantly increased compared to the control group. In contrast, the weight gain observed in mice subjected to Lactiplantibacillus plantarum F3-2 intervention was markedly lower than that of the high-fat diet group. This clearly demonstrates the positive regulatory effect of Lactiplantibacillus plantarum F3-2 on obesity induced by a high-fat diet.
    Reference: Lactiplantibacillus plantarum F3-2 and mannooligosaccharides alleviated the obesity of mice through up-regulating SCFAs and inhibiting PPARγ

    Reduce the size of fat cells and relieve excessive fat accumulation

    Experimental Study on Lactiplantibacillus plantarum F3-2

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    Conclusion:

    Probiotic Group - Significant Reduction in Adipocyte Volume

    Following the intervention with Lactiplantibacillus plantarum F3-2, the morphology of epididymal adipocytes in mice improved, with a notable decrease in cell size and an increase in the number of smaller cells.

    The average area of epididymal adipocytes in the Lactiplantibacillus F3-2 intervention group was significantly reduced compared to the NC group (p < 0.05), and there was no significant difference when compared to the orlistat group (p > 0.05).

    Reduce intra-abdominal fat, improve fatty liver conditions, and enhance hepatic glucose metabolism

    Experimental Study on Lactiplantibacillus plantarum F3-2

    NC: Control group | HFD: High-fat diet group | OR: Orlistat group | Plant F3-2: Probiotic group

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    Conclusion:

    F3-2 repairs fatty liver and restores hepatic lipid-processing function, similar to the positive drug orlistat.

    H-87 inhibits the enlargement of adipocytes and reduces body fat

    Low-fat diet feeding group (LFD), high-fat diet feeding group (HFD), probiotic + high fat diet group (H-87)

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    Experimental Study on Lactiplantibacillus plantarum H-87

    H-87 can mitigate weight gain, fat accumulation, and hyperlipidemia induced by a high-fat diet without suppressing food intake:

    • (a) H-87 effectively slows down weight gain.
    • (b) The food intake between the high-fat diet group and the high-fat diet + H-87 group is approximately the same.
    • (c) The adipocyte size in mice on a high-fat diet is significantly larger than that in mice on a low-fat diet, while H-87 supplementation can significantly inhibit the increase in adipocyte size.
    • (d) The weights of the three main white adipose tissues (eWAT, pWAT, and iWAT) in mice on a high-fat diet are significantly increased, whereas H-87 can effectively suppress weight gain in these mice.
    • (e) H-87 supplementation can significantly reduce serum triglyceride and LDL levels.

    H-87 reduces liver lipogenesis

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    Experimental Study on Lactiplantibacillus plantarum H-87

    Low-fat diet fed group (LFD), high-fat diet fed group (HFD), probiotics + high-fat diet group (H-87):
    A high-fat diet significantly increases liver weight and triglyceride (TG) levels, while H-87 supplementation can markedly reduce liver weight, liver TG, and cholesterol (CHOL) in mice subjected to a high-fat diet, thereby decreasing hepatic fat accumulation.

    Frequently Asked Questions

    ❓ What are the main probiotic strains in this premix?
    The main strains included are Lactiplantibacillus plantarum F3-2, Lactiplantibacillus plantarum H-87, Lactiplantibacillus plantarum YZX21, Lacticaseibacillus casei YRL577, Lacticaseibacillus paracasei G15, and Bifidobacterium animalis subsp. lactis BA-C53.
    ❓ What are the primary health benefits of this probiotic blend?
    This formulation helps lower body weight and BMI, reduce waist circumference, reduce visceral fat, relieve high-fat diet-induced obesity, and reduce overall food intake.
    ❓ How do the strains F1-7 and YZX21 regulate blood sugar?
    F1-7 and YZX21 work by increasing the level of GLP-1, which promotes insulin secretion in the body. They up-regulate the glucagon gene to regulate blood sugar bidirectionally, helping to relieve both hyperglycemia and hypoglycemia.
    ❓ How does Lactiplantibacillus plantarum F3-2 affect body fat and liver health?
    F3-2 has been shown to significantly reduce adipocyte (fat cell) volume and reduce intra-abdominal fat. It also helps repair fatty liver and restore hepatic lipid-processing function, showing positive regulatory effects against high-fat diet-induced obesity.
    ❓ What specific benefits does Lactiplantibacillus plantarum H-87 provide?
    H-87 mitigates weight gain, fat accumulation, and hyperlipidemia without suppressing food intake. It inhibits the enlargement of adipocytes, suppresses weight gain in major white adipose tissues (eWAT, pWAT, and iWAT), reduces liver weight, and lowers serum triglyceride, cholesterol, and LDL levels.
    ❓ What are the shelf life and recommended storage conditions?
    The product has a shelf life of 24 months when stored under recommended conditions of -18℃ or below.

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