Anti-aging & Inflammation Relief/ZC-AAI/Probiotics Premix/500B
Anti-aging probiotics blend solution
ZC-AAI:Anti-aging & Inflammation Relief
Shelf life: 24 months
Storage conditions: Stored at -18℃or below
Main Strains
Bioyitech's Micro-Ecological Anti-Aging Solution
F1-7/YZX21 elevates GLP-1 and PYY levels, thereby stimulating insulin secretion in a glucose-dependent manner
Experiments with Lactobacillus F1-7/Plant YZX21 Related Strains
Control:Hyperglycaemia group Rhamnose LGG:Probiotics group
Bifidobacterium lactisF1-7:Probiotics group Plant YZX21:Probiotics group
Role of F1-7, YZX21:
Increase the level of GLP-1, thus promoting the release of insulin from the pancreas,
blocking glucagon secretion, and lowering postprandial blood glucose.
G15 modulates glycemia by upregulating GRP43 and secreting GLP-1/PYY
Conclusion: G15 parietal cheese can effectively improve glucose tolerance and prevent hyperglycaemia in patients with type II diabetes mellitus.
① (B/b) glucose tolerance is a recognised diagnostic criterion for insulin resistance in T2D. After 6 weeks of treatment, glucose tolerance was effectively restored in all treatment groups.
② (C/D) Insulin and glucagon are sensitive parameters for the diagnosis of diabetes mellitus and reference indexes for blood glucose control, and G15 reduced insulin and glucagon concentrations to a large extent.
Conclusion: The protein expressionlevel of MUC-2 was lowest in themodel group and significantlyincreased in the normal andintervention groups.
The most significant up-regulation ofMUC-2 protein level was found afterthe intervention of KGM+F1-7combination .
Serum levels of the endotoxin LPS areconsidered to be a potential indicator ofincreased intestinal permeability and arestrongly correlated with intestinal permeability.
As shown in the figure, serum endotoxin levelswere significantly increased in the sham groupcompared to the OVX group, demonstratingthat estrogen deficiency increases intestinalpermeability.
Both significantly reduced serum endotoxinlevels (p<0.05) by probiotic F1-7 intervention,which further suggests that probiotic F1-7reduced intestinal permeability
Lacticaseibacillus paracasei X11 can repair intestinal tissue
Compared to the control group, the model group's intestinal tract exhibited a loss of structural integrity, with disordered intestinal epithelial folds and a near-complete disappearance of the muscularis externa. In contrast, the intervention group displayed relatively regular intestinal mucosal folds and an intact muscularis externa.
Studies have shown that F1-7 has a significant anti-inflammatory effect.
Schematic diagram of histochemistry of theexpression of inflammatory factor-relatedindexes in the aorta of mice, using AS as acontrol:
Groups F1-7: TLR4-positive areas weresignificantly reduced, reducing the expressioncontent of MYD88 in the aortic sinus andimproving inflammatory expression;Group KO:TLR4-positive areas weresignificantly reduced, reducing the expressioncontent of MYD88 in the aortic sinus andimproving inflammatory expression.
Group KF: The most significant reduction ofTLR4-positive areas was achieved, reducingthe expression content of MYD88 in theaortic sinus had the most significant effectand improving inflammatory expression.