Weight management/Probiotics Premix/500B

F1-7 and YZX21 increase the level of GLP-1, thus promoting the secretion of insulin in the body, and up-regulate glucagon gene, regulate blood sugar bidirectional, and relieve the phenomenon of hyperglycemia or hypoglycemia.

The data presented in the figure indicates that after a period of feeding, the body weight of mice in the high-fat diet groupsignificantly increased compared to the control group. In contrast, the weight gain observed in mice subjected to Lactiplantibacillus plantarum F3-2 intervention was markedly lower than that of the high-fat diet group. This clearly demonstrates the positive regulatory effect of Lactiplantibacillus plantarum F3-2 on obesity induced by a high-fat diet.

Reference: Lactiplantibacillus plantarum F3-2 and mannooligosaccharides alleviated the obesity of mice through up-regulating SCFAs and inhibiting PPARγ

Experimental Study on Lactiplantibacillus plantarum F3-2

Probiotic Group - Significant Reduction in Adipocyte Volume

Following the intervention with Lactiplantibacillusplantarum F3-2, the morphology of epididymaladipocytes in mice improved, with a notable decrease incell size and an increase in the number of smaller cells.

The average area of epididymal adipocytes in theLactiplantibacillus F3-2 intervention group wassignificantly reduced compared to the NC group (p <0.05), and there was no significant difference whencompared to the orlistat group (p > 0.05)

Experimental Study on Lactiplantibacillus plantarum F3-2

NC: Control group HFD: High-fat diet group OR: Orlistat group Plant F3-2: Probiotic group

Conclusion:
F3-2, repairs fatty liver andrestores hepatic lipid-processingfunction, similar to the positivedrug orlistat.

Low-fat diet feeding group (LFD), high-fat diet feeding group (HFD), probiotic + high fat diet group (H-87)

H-87 can mitigate weight gain, fat accumulation, and hyperlipidemiainduced by a high-fat diet without suppressing food intake:

(a) H-87 effectively slows down weight gain.

(b) The food intake between the high-fat diet group and the high-fatdiet + H-87 group is approximately the same.

(c) The adipocyte size in mice on a high-fat diet is significantly largerthan that in mice on a low-fat diet, while H-87 supplementation cansignificantly inhibit the increase in adipocyte size.

(d) The weights of the three main white adipose tissues (eWAT,pWAT, and iWAT) in mice on a high-fat diet are significantlyincreased, whereas H-87 can effectively suppress weight gain in thesemice.

(e) H-87 supplementation can significantly reduce serum triglycerideand LDL levels.

Low-fat diet fed group (LFD), high-fat diet fed group (HFD), probiotics + high-fat diet group (H-87) A high-fat diet significantly increases liver weight and triglyceride (TG) levels, while H-87 supplementation can markedly reduce liver weight, liver TG, and cholesterol (CHOL) in mice subjected to a high-fat diet, thereby decreasing hepatic fat accumulation.